The NATIONAL FIREFIGHTER CANCER SYMPOSIUM (NFCS) will bring together members from the scientific, academic, firefighting, government, and labor/management communities to support the reduction of cancer risk in the U.S. fire service. Together, the mission is to extinguish cancer. The 2021 NFCS will be jointly hosted by the First Responder Center for Excellence (FRCE) and the Firefighter Cancer Initiative (FCI). The event will focus on the most current research and cancer prevention practices in the fire service.